The researchers confirmed the importance for the formation of NO NET by exposing mice to Klebsiella pneumoniae bacteria. Neutrophils in the lungs led in the control mice and animals lacking NE. But the mice lacking neutrophils could produce NET to trap insects.An important question to answer now, the researchers say, is how NE and MPO travel to the nucleus. The granules can fuse with the nuclear membrane, directly or burst and release enzymes into the cytoplasm, where they move to the nucleus.
Papayannopoulos, V. 2010. J. Cell Biol. doi: 10.1083/jcb.201006052.
Once the generic version is approved, it is not clear how long to wait for Barr on the market. Downey expressed optimism Wednesday that the decision will be maintained, allowing a patent on Prozac expired in February 2001.
But why Lilly is to test the drug in pediatric cases, the patent may be extended for six months, until August 2001.
Source: http://www.la-logistique.com/?p=558
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